Current Issues of Pharmacy and Medical Sciences

Protective role of quercetinum in mercury exposure cardiotoxity

Curr Issues Pharm Med Sci., Vol. 32, No. 2, 63-66

Rostyslav F. Kaminsky

O.O. Bogomolets National Medical University, Department of Histology and Embryology, Kyiv, Ukraine, T. Shevchenko boulevard 13, Kyiv, 01601


https://doi.org/10.2478/cipms-2019-0012

Abstract

The article describes the remediation of myocardium structure characteristics provided by Quercetinum under the influence of 0.01 LD50 mercury chloride (II) in rats at chronic exposure. Ultrastructural and metabolic reorganization of myocardium tissue was studied by electron microscopic and histochemical techniques. Quercetinum reduces energy imbalance in the myocardium, shows membrane-stabilizing activity, and promotes stabilization and normalization of the function of membranes by direct biochemical interaction of the membrane organelles of the body’s cells.

Keywords

quercetinum, mercury chloride, chronic exposure, myocardium, rats.

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