Current Issues of Pharmacy and Medical Sciences

Sever hepatitis induced by Epstein-Barr virus: case series

Curr Issues Pharm Med Sci., Vol. 31, No. 1, 44-46

Mohammad Reza Hasanjani Roushan, Mostafa Javanian,
Zahra Aliramaji, Soheil Ebrahimpournia

Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran

DOI: 10.1515/cipms-2018-0010


Epstein-Barr virus (EBV) is a causative agent of infectious mononucleosis syndrome. This infection often resolves over a period of several months without outcomes, but may occasionally be complicated by a great variety of neurologic, hepatic, hematologic and respiratory complications. In the current report, we present the case histories of three patients with acute hepatitis following EBV infection when previously healthy. The patients showed fever, nausea, weakness, as well as yellowing of the skin, and then in the course of examination, sore throat. They were managed supportively and their clinical condition improved. Liver function tests such as ALT, AST, ALP, were undertaken and bilirubin were elevated. The serological tests for EBV infection were consistent with the acute phase of infection. The monospot test was also positive. The patients were managed supportively, and their critical condition was improved.


Epstein-Barr virus, hepatitis, serologic tests.


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