
Evaluation of the antioxidant activity of extracts and flavonoids obtained from Bunium alpinum Waldst. & Kit. (Apiaceae) and Tamarix gallica L. (Tamaricaceae)
Curr Issues Pharm Med Sci., Vol. 30, No. 1, 5-8
Mostefa Lefahal1, Nabila Zaabat1, Lakhdar Djarri1, Merzoug Benahmed2,
Kamel Medjroubi1, Hocine Laouer3, Salah Akkal1*
1Université de Constantine, Unité de Recherche Valorisation des Ressources Naturelles Molécules Bioactives et Analyses Physico-Chimiques et Biologiques, Département de Chimie, Facultés des Sciences Exactes, Algérie
DOI: https://doi.org/10.1515/cipms-2017-0001
Abstract
The aim of the present work was to evaluate the antioxidant activity of extracts and four flavonoids that had been isolated from the aerial parts of Bunium alpinum Waldst. et Kit. (Apiaceae) and Tamarix gallica L. (Tamaricaceae). In this work, the four flavonoids were first extracted via various solvents, then purified through column chromatography (CC) and thin layer chromatography (TLC). The four compounds were subsequently identified by spectroscopic methods, including: UV, mass spectrum 1H NMR and 13C NMR. The EtOAc extract of Bunium alpinum Waldst. et Kit yielded quercetin-3-O-β-glucoside (3',4',5,7-Tetrahydroxyflavone-3-β-D-glucopyranoside) (1), while the EtOAc and n-BuOH extracts of Tamarix gallica L afforded 3,5,3’-trihydroxy-7,4’-dimethoxyflavone (2), 3,5,7-trihydroxy-4’-methoxyflavone (3) and 5-hydroxy-3,7,4’-trimethoxyflavone (4).
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