Current Issues of Pharmacy and Medical Sciences

The use of a freeze-dried extract of Ligusticum mutellina in a cosmetic cream with potential antioxidant properties

Curr Issues Pharm Med Sci., Vol. 29, No. 4, 155-157

Baj Tomasz1, Sieniawska Elwira1, Kubiak Bartłomiej2, Partyka Danuta2

1 Department of Pharmacognosy with Medical Plant Unit, Medical University of Lublin, Poland
2 Department of Pharmaceutical Technology, Faculty of Pharmacy, Nicolaus Copernicus University in Toruń, Poland

DOI: 10.1515/cipms-2016-0032

Full Text


The aim of this work was to develop a cream formulation with potential antioxidant properties. Herein, a freeze-dried extract of Ligusticum mutellina was used as a source of active compounds. The proposed qualitative composition of the cream was characterized by a good polyphenolic compounds release profile. Of note, the highest R2adj values were obtained for the Korsmeyer-Peppas and Higuchi models (0.9159 and 0.9226, respectively). These results indicate that a freeze-dried extract of L. mutellina, due to its retained high phenolic acids content, could become a key component in antioxidant creams.


cosmetic formulation, phenolic acids, antioxidant properties.


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