Current Issues of Pharmacy and Medical Sciences

The connection of hydronephrosis and microcirculation deterioration

Curr Issues Pharm Med Sci., Vol. 29, No. 3, 132-134

Dmytro Vorobets

Department of Urology, Danylo Halytsky Lviv National Medical University, 69 Pekarska, 79010 Lviv, Ukraine

DOI: 10.1515/cipms-2016-0027


In this study, we have analyzed the influence of hydronephrosis upon the microcirculation system, in situations of pyeloureteral junction obstruction. Herein, bulbar conjunctiva has been chosen as the object of this biomicroscopic study because of its simplicity and the method availability in clinic practice. In fulfilling this work, we ascertained the connections between extravascular, intravascular, vascular and general conjunctival indices of the patients before radical and paliatic correction of the pyeloureteral junction obstruction (i.e. by open and laparoscopic pyeloplasty, endopyelotomy, laser resection and balloon dilatation). We concluded that, apart from the proved deterioration of kidney function, systemic deteriorations of microcirculation may be observed in situations of clinically marked hydronephrosis, according to the results of radioisotope renography and excretory urography.

Full Text


pyeloureteral junction obstruction, conjunctival index, microcirculation.


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