Current Issues of Pharmacy and Medical Sciences

Furochinoline alkaloids in plants from Rutaceae family – a review

Curr Issues Pharm Med Sci., Vol. 29, No. 1, p.33-38

Aldona Adamska-Szewczyk1*, Kazimierz Glowniak2, Tomasz Baj2

Hibiscus Pharmacy, 26 Puławska Str, 02-512 Warszawa, Poland
Department Pharmacognosy with Medical Plant Unit, Medical University of Lublin, 1 Chodzki , 20-093 Lublin, Poland

DOI:  10.1515/cipms-2016-0008



Over the past five years, phytochemical and pharmacological studies have been conducted on material extracted from members of the Rutaceae family. In such work, new furochinoline-structured alkaloids were isolated from Ruta sp. and Dictamnus sp. Beyond the aforementioned, other substances with promising activity were isolated from the less-known species of Zanthoxylum, Evodia, Lonchocarpus, Myrthopsis and Teclea. Currently used forms of extraction, as well as methods of isolation and detection, allow the obtaining of pure, biologically active compounds. Many of these have anti-fungal, anti-bacterial and anti-plasmodial properties. Others are still being researched as potential drugs, which, in future, may be used in treating those afflicted with HIV and cancer. This article is designed to give the readers a thorough review of the active natural products from the Rutaceae family.




Rutaceae, furochinoline alkaloids, dictamnine, skimmianine, kokusaginine, activity, Zanthoxylum, Evodia, Conchocarpus, Myrthopsis, Teclea.


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