Littoral cell angioma mimicking metastatic tumors
Curr Issues Pharm Med Sci., Vol. 28, No. 4, Pages 247-249
Justyna Szumilo1, Anna Ostrowska1*, Malgorzata Zdunek1, Slawomir Rudzki2,
Tomasz Chroscicki3, Elzbieta Czekajska-Chehab4, Franciszek Burdan3
Littoral cell angioma is a rare primary, vascular tumor thought to originate from the endothelial cells lining the sinuses of the splenic red pulp (the “littoral cells”). It is a benign, usually asymptomatic lesion diagnosed incidentally. Ultrasound and tomography appearance is not characteristic and histopathological examination is required. This work provides a case-study of littoral cell angioma which was seen in a 55-year-old female who complained of non-specific upper abdominal pain. Computed tomography revealed multiple hypo-attenuated splenic lesions suggestive for metastasis. A splenectomy was performed and routine microscopic examination supported by immunohistochemistry reactions with CD68, CD34 and CD31 showed littoral cell angioma.