Current Issues of Pharmacy and Medical Sciences

Synthesis of new derivatives of 9-(2-pyridyl)-3-aryl(arylalkyl)-2,4,5(9H)trioxo- 7,8-dihydroimidazo[1,2-a][1,3,5]triazepine

Curr Issues Pharm Med Sci., Vol. 27, No. 1, Pages 8-9

Marzena Rządkowska1, Elżbieta Szacoń1, Maria Zuń2

Chair and Department of  Synthesis and  Chemical Technology of  Pharmaceutical Substances with Computer Modeling Unit, Faculty of Pharmacy with Division of Medical Analytics, Medical University of Lublin, 4a Chodźki St., 20-093 Lublin, Poland

Chair and Department of Applied Pharmacy, Faculty of Pharmacy, Medical University of Lublin, 1 Chodźki St, 20-093 Lublin, Poland

DOI: 10.2478/cipms-2014-0002


A series of new derivatives of  9-(2-pyridyl) -3-aryl(arylalkyl)-2,4,5(9H)trioxo-7,8-dihydroimidazo [1,2-a][1,3,5]triazepine was obtained by condensation of 1-(2-pyridyl)imida-zolidine-2-ylidene]-3-aryl(arylalkyl) with diethyl oxalic acid ester. Considering the structure of the obtained compounds, it can be expected that these compounds can reveal pharmacological activity.


Full Text


1-[1-(2-pyridyl)imidazolidine-2-ylidene]-3-aryl(arylalkyl) derivatives, diethyl oxalic acid ester


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