Current Issues of Pharmacy and Medical Sciences

State of knowledge about drugs used during pregnancy and their toxicity to the fetus – preliminary report

Current Issues in Pharmacy and Medical Sciences Vol. 26, No. 2, Pages 211-214

IRENA MAŁGORZATA DUŚ1, MARIA LEPUCKA2, LIDIA HIRNLE2, MAŁGORZATA RADWAN-OCZKO1

1Department of Periodontology, Unit of Oral Pathology, Faculty of Dentistry, Wroclaw Medical University, Poland
2Department of Gynecology and Obstetrics, Faculty of Health Sciences, Wroclaw Medical University, Poland

DOI: 10.12923/j.2084-980X/26.2/a.20

 

Abstract

Most drugs pass through the placenta because of its small weight. What remains inadequate, is patients’ awareness of pharmacotherapy during pregnancy. There are not so many experiments showing the knowledge about pharmacotherapy during pregnancy among women. In the present study authors wanted to demonstrate what is the knowledge of women about drugs toxicity in FDA pregnancy categories, the use of prescription drugs and biological products, and what kind of drugs, supplements of diet and herbal products were used by patients during pregnancy. The aim was also to reveal knowledge about drugs toxicity on fetus. Questionnaire survey was anonymous, and done by a midwife 1-3 days after parturition. Patients were women from region of Lower Silesia (Poland), who chose to give birth in the Clinic of Gynecology and Obstetrics, Chalubinskiego Street in Wroclaw. Research resulted in 60 questionnaires received from women. Percentage of patients, who had been taking supplementation with folic acid and vitamins reached 77%. As much as 45% of women who took part in research had used pharmacotherapy during pregnancy. From all women, 17% declared to have taken herbal preparations for common cold, fever, cough. Result of the study revealed that 23% of women who took part in the study knew about the FDA division of drugs used during pregnancy. The knowledge about possible teratogenic effect of the drugs is not yet well established among women after parturition. Special observations have to be done among pregnant women for broadening the knowledge about pharmacotherapy in pregnancy and women’s treatment habits during pregnancy.

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Keywords

drug therapy, herb-drug interactions, drug toxicity, pregnancy pharmacology

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