Current Issues of Pharmacy and Medical Sciences

Antidepressant drugs and cardio-vascular system

Current Issues in Pharmacy and Medical Sciences Vol. 26, No. 2, Pages 144-147

GRZEGORZ OPIELAK1, BARBARA MADEJ-CZERWONKA1, JAKUB PIOTRKOWICZ1,
ŁUKASZ SZESZKO1, WOJCIECH DWORZAŃSKI1, CEZARY KOWALSKI2, SYLWIA OPIELAK2,
MATEUSZ SZYMAŃSKI1, MONIKA CENDROWSKA-PINKOSZ1

1Chair and Department of Human Anatomy, Medical University of Lublin, Poland
2Chair of Pre-clinical Veterinary Sciences, Department of Pharmacology, University of Life Sciences, Lublin, Poland

DOI: 10.12923/j.2084-980X/26.2/a.05

 

Abstract

Depression is becoming a more and more frequent problem in highly – developed countries. There exist many factors predisposing to the occurrence of the disease. To most commonly mentioned, are organic CNS damage, genetic factors, disorders in neurotransmitters, and hormone dysfunctions. The disease disturbs the functioning of many organs and systems, causing the increase in the risk of the progression of the coronary disease and venous thrombotic- embolic illness. Antidepressants constitute the heterogenic group in terms of their chemical structure and mechanisms of action. Today it is known that applying them indeed increases the risk of the development of disadvantageous changes in the cardio-vascular system. In this study, an attempt of synthetic analysis of the influence of medicines applied in the treatment of depression on cardiovascular diseases was undertaken. 

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Keywords

depression, antidepressant drugs, cardio-vascular system

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