Current Issues of Pharmacy and Medical Sciences

Examination of salivary proteins as biomarkers of pathological conditions. Literature review

Current Issues in Pharmacy and Medical Sciences Vol. 26, No. 1, Pages 71-75


Oral Surgery Department, Medical University of Lublin, Poland

DOI: 10.12923/j.2084-980X/26.1/a.16



Saliva is universally available biofluid, easy to collect. Comprehensive analysis and identification of the proteomic content of human saliva may contribute to the understanding of oral pathophysiology and provide a foundation for the recognition of potential biomarkers of human disease. These features make it an ideal biological material for the early detection of many diseases of different origin, and enable non-invasive diagnostics. The presence of protein markers in saliva was found with usage of capillary electrophoresis and mass spectrometry.


salivary proteins, salivary diagnostics, chromatography, mass spectrometry


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