Current Issues of Pharmacy and Medical Sciences

Screening of antifungal activity of Rumex L. species

Annales UMCS, Sectio DDD, Pharmacia, Vol. XXIV, N 4, 10

URSZULA KOSIKOWSKA1, MAGDALENA WEGIERA2, HELENA D. SMOLARZ2, ANNA MALM1

Department of Pharmaceutical Microbiology, Medical University of Lublin, Lublin, Poland

Department of Pharmaceutical Botany, Medical University of Lublin, Lublin, Poland

Abstract

Antifungal activity of the ethanol extracts obtained from fruits, leaves and roots of six species of Rumex L. (Racetosa L., R. acetosella L., R. confertus Willd., R. crispus L., R. hydrolapathum Huds. and R. obtusifolius L.) growing in Poland against the reference strains yeasts, dermatophytes and moulds was assessed by agar dilution method allowing for determination of minimal inhibitory concentration (MIC). The extracts from fruits of R. confertusR. crispusR. hydrolapathum and R. obtusifolius were the most active, showing moderate activity against Candida spp. and Trichophyton mentagrophytes ATCC 9533 with MIC = 250-500 μg/mL; no activity against Aspergillus niger ATCC 16404 was found. The obtained data indicate the fruits from the above Rumex species may be regarded as alternative or adjunctive agents in treatment of superficial mycoses.

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Keywords

Rumex L., ethanol extracts, fruits, leaves, roots, antifungal activity

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